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International consumers often purchase drugs online from online pharmacies in their own countries, or those located in other nations such as India, Pakistan and the Philippines. Some of these pharmacies require prescriptions, while others do not. Of those which do not require prescriptions, some do ask the customer to fill in a health questionnaire with their order. Drugs available online are often produced by well-known manufacturers such as Pfizer, Wyeth, Roche, and generic Indian drugmakers Cipla and Ranbaxy and Teva Pharmaceutical Industries of Israel. It is a fairly common practice for North American and European visitors to countries like Thailand, India and South Africa to purchase and bring home affordable medications for themselves, family members and/or friends.[citation needed] Savings can be significant, often exceeding 80 percent compared to the same medications available in their home countries. Travellers may avoid possible difficulties inherent to physically going through customs with their medication purchases by mailing the drugs to their home so they receive them upon their return. o save money, millions of uninsured and underinsured U.S. consumers purchase drugs from online pharmacies in Canada, India, the UK and other countries and receive their purchases by mail.

Especially for uninsured Americans taking prescription drugs for chronic health conditions, a major attraction of online pharmacies abroad is that nearly every country, except the U.S., controls its drug prices. Shoppers can easily obtain 50 to 80 percent or more savings at foreign pharmacies, in comparison to US prices. Very rarely are these orders investigated because U.S. authorities are much more worried about controlling illegal pharmacies in the U.S., not consumers themselves. In fact, the Washington Post reported that ".

millions of Americans have turned to Mexico and other countries in search of bargain drugs.U.S. Customs estimates 10 million U.S. citizens bring in medications at land borders each year. An additional 2 million packages of pharmaceuticals arrive annually by international mail from Thailand, India, South Africa and other points. Still more packages come from online pharmacies in Canada. Until about 2005, American consumers looking abroad most commonly turned to Canadian pharmacies for affordable medications.[citation needed] Today, many consumers head to online pharmacies in India, South Africa and other countries where drug prices are often lower than in Canada.